BDBM50200111 CHEMBL3981566
SMILES: CC(=O)Nc1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=VNFSDDHWIVSKFW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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O-GlcNAc Transferase (OGT) (Homo sapiens (Human)) | BDBM50200111 (CHEMBL3981566) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Noncompetitive inhibition of OGT (unknown origin) using variable UDP-GlcNAc levels and fixed CKII peptide level by UDP-Glo glycosyltransferase assay | J Med Chem 60: 263-272 (2017) Article DOI: 10.1021/acs.jmedchem.6b01237 BindingDB Entry DOI: 10.7270/Q20G3N47 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-GlcNAc Transferase (OGT) (Homo sapiens (Human)) | BDBM50200111 (CHEMBL3981566) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 3.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Noncompetitive inhibition of OGT (unknown origin) using fixed UDP-GlcNAc levels and variable CKII peptide level by UDP-Glo glycosyltransferase assay | J Med Chem 60: 263-272 (2017) Article DOI: 10.1021/acs.jmedchem.6b01237 BindingDB Entry DOI: 10.7270/Q20G3N47 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-GlcNAc Transferase (OGT) (Homo sapiens (Human)) | BDBM50200111 (CHEMBL3981566) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of OGT (unknown origin) assessed as reduction in GlcNAc transfer to CKII peptide incubated for 60 mins by HPLC method | J Med Chem 60: 263-272 (2017) Article DOI: 10.1021/acs.jmedchem.6b01237 BindingDB Entry DOI: 10.7270/Q20G3N47 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human)) | BDBM50200111 (CHEMBL3981566) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of ppGalNAcT2 (unknown origin) in presence of OGT, EA2 and UDP-GlcNAc incubated for 25 mins at 37 degC | J Med Chem 60: 263-272 (2017) Article DOI: 10.1021/acs.jmedchem.6b01237 BindingDB Entry DOI: 10.7270/Q20G3N47 | |||||||||||
More data for this Ligand-Target Pair |