null

SMILES: CCCC(=O)N1CCc2[nH]nc(Nc3cccc(C)c3)c2C1

InChI Key: InChIKey=KCRYJKJMBMOMAP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50200437 (CHEMBL3979220) Show SMILES CCCC(=O)N1CCc2[nH]nc(Nc3cccc(C)c3)c2C1 Show InChI InChI=1S/C17H22N4O/c1-3-5-16(22)21-9-8-15-14(11-21)17(20-19-15)18-13-7-4-6-12(2)10-13/h4,6-7,10H,3,5,8-9,11H2,1-2H3,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50200437 (CHEMBL3979220) Show SMILES CCCC(=O)N1CCc2[nH]nc(Nc3cccc(C)c3)c2C1 Show InChI InChI=1S/C17H22N4O/c1-3-5-16(22)21-9-8-15-14(11-21)17(20-19-15)18-13-7-4-6-12(2)10-13/h4,6-7,10H,3,5,8-9,11H2,1-2H3,(H2,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair