BDBM50201176 CHEMBL3943243

SMILES: COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3

InChI Key: InChIKey=ILONTPDVQVKFCL-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50201176 (CHEMBL3943243) Show SMILES COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3 Show InChI InChI=1S/C25H34N4O2/c1-31-23-14-7-6-13-20(23)22-18-29-16-10-8-12-19(30)11-5-3-2-4-9-15-26-25-27-17-21(22)24(29)28-25/h6-7,13-14,17-19,30H,2-5,8-12,15-16H2,1H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50201176 (CHEMBL3943243) Show SMILES COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3 Show InChI InChI=1S/C25H34N4O2/c1-31-23-14-7-6-13-20(23)22-18-29-16-10-8-12-19(30)11-5-3-2-4-9-15-26-25-27-17-21(22)24(29)28-25/h6-7,13-14,17-19,30H,2-5,8-12,15-16H2,1H3,(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201176 (CHEMBL3943243) Show SMILES COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3 Show InChI InChI=1S/C25H34N4O2/c1-31-23-14-7-6-13-20(23)22-18-29-16-10-8-12-19(30)11-5-3-2-4-9-15-26-25-27-17-21(22)24(29)28-25/h6-7,13-14,17-19,30H,2-5,8-12,15-16H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of human MerTK kinase domain (1585 to 3000 residues) expressed in HEK293 cells co-expressing rat EGFR LBD assessed as inhibition of EGF-st...				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50201176 (CHEMBL3943243) Show SMILES COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3 Show InChI InChI=1S/C25H34N4O2/c1-31-23-14-7-6-13-20(23)22-18-29-16-10-8-12-19(30)11-5-3-2-4-9-15-26-25-27-17-21(22)24(29)28-25/h6-7,13-14,17-19,30H,2-5,8-12,15-16H2,1H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50201176 (CHEMBL3943243) Show SMILES COc1ccccc1-c1cn2CCCCC(O)CCCCCCCNc3ncc1c2n3 Show InChI InChI=1S/C25H34N4O2/c1-31-23-14-7-6-13-20(23)22-18-29-16-10-8-12-19(30)11-5-3-2-4-9-15-26-25-27-17-21(22)24(29)28-25/h6-7,13-14,17-19,30H,2-5,8-12,15-16H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of MerTK (unknown origin) by microfluidic capillary electrophoresis assay				ACS Med Chem Lett 7: 1044-1049 (2016) Article DOI: 10.1021/acsmedchemlett.6b00221 BindingDB Entry DOI: 10.7270/Q208679K
					More data for this Ligand-Target Pair