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BDBM50204653 CHEMBL3945429

SMILES: NC(=O)c1cc(ccc1O)-c1cn2cc(F)ccc2n1

InChI Key:

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204653   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificty protein kinase CLK1


(Homo sapiens (Human))
BDBM50204653
PNG
(CHEMBL3945429)
Show SMILES NC(=O)c1cc(ccc1O)-c1cn2cc(F)ccc2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Universit£ Paris-Saclay

Curated by ChEMBL


Assay Description
Inhibition of CLK1 (unknown origin)


Eur J Med Chem 123: 105-114 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.040
BindingDB Entry DOI: 10.7270/Q2GT5Q4M
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50204653
PNG
(CHEMBL3945429)
Show SMILES NC(=O)c1cc(ccc1O)-c1cn2cc(F)ccc2n1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



Universit£ Paris-Saclay

Curated by ChEMBL


Assay Description
Inhibition of DYRK1A (unknown origin)


Eur J Med Chem 123: 105-114 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.040
BindingDB Entry DOI: 10.7270/Q2GT5Q4M
More data for this
Ligand-Target Pair
Casein kinase I delta/epsilon


(Homo sapiens (Human))
BDBM50204653
PNG
(CHEMBL3945429)
Show SMILES NC(=O)c1cc(ccc1O)-c1cn2cc(F)ccc2n1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ Paris-Saclay

Curated by ChEMBL


Assay Description
Inhibition of CK1 delta/epsilon (unknown origin)


Eur J Med Chem 123: 105-114 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.040
BindingDB Entry DOI: 10.7270/Q2GT5Q4M
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (Human))
BDBM50204653
PNG
(CHEMBL3945429)
Show SMILES NC(=O)c1cc(ccc1O)-c1cn2cc(F)ccc2n1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ Paris-Saclay

Curated by ChEMBL


Assay Description
Inhibition of GSK-3 alpha/beta (unknown origin)


Eur J Med Chem 123: 105-114 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.040
BindingDB Entry DOI: 10.7270/Q2GT5Q4M
More data for this
Ligand-Target Pair