BDBM50208090 (1S,8S,11S,13S,16S,17R)-8-tert-butyl-17-hydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.0^{1,11}.0^{3,7}.0^{7,11}.0^{13,17}]nonadecane-5,6,15,18-tetrone::CHEMBL376302
SMILES: C[C@@H]1C(=O)O[C@H]2C[C@@]34C5C[C@@H](C(C)(C)C)C33C(OC(=O)C3=O)O[C@]4(C(=O)O5)[C@@]12O
InChI Key: InChIKey=RHHKORAMUFJXGE-FHOKLSSGSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM50208090 ((1S,8S,11S,13S,16S,17R)-8-tert-butyl-17-hydroxy-16...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at human alpha1GlyR expressed in HEK293 cells by FMP assay | J Med Chem 50: 1610-7 (2007) Article DOI: 10.1021/jm070003n BindingDB Entry DOI: 10.7270/Q2GB23QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM50208090 ((1S,8S,11S,13S,16S,17R)-8-tert-butyl-17-hydroxy-16...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at human alpha1betaGlyR expressed in HEK293 cells by FMP assay | J Med Chem 50: 1610-7 (2007) Article DOI: 10.1021/jm070003n BindingDB Entry DOI: 10.7270/Q2GB23QT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine receptor subunit alpha-2 (Homo sapiens (Human)) | BDBM50208090 ((1S,8S,11S,13S,16S,17R)-8-tert-butyl-17-hydroxy-16...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Activity at human alpha2GlyR expressed in HEK293 cells by FMP assay | J Med Chem 50: 1610-7 (2007) Article DOI: 10.1021/jm070003n BindingDB Entry DOI: 10.7270/Q2GB23QT | |||||||||||
More data for this Ligand-Target Pair |