null

SMILES: CC1(OC(=CC1=O)C(O)=O)c1ccccc1

InChI Key: InChIKey=DFDGRKNOFOJBAJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50208138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at N-terminal HA-tagged GPR109b receptor transfected in forskolin-stimulated cells assessed as cAMP accumulation by flashplate assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109a (unknown origin) assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Agonist activity at HCA2 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISA				Bioorg Med Chem 23: 4013-25 (2015) Article DOI: 10.1016/j.bmc.2015.02.018 BindingDB Entry DOI: 10.7270/Q22N558B
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	520	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109a (unknown origin) assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at N-terminal HA-tagged GPR109a receptor transfected in forskolin-stimulated cells assessed as cAMP accumulation by flashplate assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Agonist activity at HCA3 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISA				Bioorg Med Chem 23: 4013-25 (2015) Article DOI: 10.1016/j.bmc.2015.02.018 BindingDB Entry DOI: 10.7270/Q22N558B
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair