BDBM50209149 1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazole-5-carbonyl)-piperidine-3-carboxylic acid::CHEMBL245734

SMILES: OC(=O)C1CCCN(C1)C(=O)c1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1

InChI Key: InChIKey=WBRHCOIAJKWTPZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50209149 (1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...) Show SMILES OC(=O)C1CCCN(C1)C(=O)c1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C21H19N3O3S/c25-20(24-7-2-3-12(10-24)21(26)27)15-5-1-4-14-16(15)9-17-18(22-23-19(14)17)13-6-8-28-11-13/h1,4-6,8,11-12H,2-3,7,9-10H2,(H,22,23)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50209149 (1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...) Show SMILES OC(=O)C1CCCN(C1)C(=O)c1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C21H19N3O3S/c25-20(24-7-2-3-12(10-24)21(26)27)15-5-1-4-14-16(15)9-17-18(22-23-19(14)17)13-6-8-28-11-13/h1,4-6,8,11-12H,2-3,7,9-10H2,(H,22,23)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt1 by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50209149 (1-(3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazo...) Show SMILES OC(=O)C1CCCN(C1)C(=O)c1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C21H19N3O3S/c25-20(24-7-2-3-12(10-24)21(26)27)15-5-1-4-14-16(15)9-17-18(22-23-19(14)17)13-6-8-28-11-13/h1,4-6,8,11-12H,2-3,7,9-10H2,(H,22,23)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of c-Kit by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair