BDBM50209157 (3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-carbamic acid ethyl ester::CHEMBL396586

SMILES: CCOC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1

InChI Key: InChIKey=ODAFQKIWRIFCIF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50209157 ((3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-...) Show SMILES CCOC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C17H15N3O2S/c1-2-22-17(21)18-14-5-3-4-11-12(14)8-13-15(19-20-16(11)13)10-6-7-23-9-10/h3-7,9H,2,8H2,1H3,(H,18,21)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of c-Kit by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50209157 ((3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-...) Show SMILES CCOC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C17H15N3O2S/c1-2-22-17(21)18-14-5-3-4-11-12(14)8-13-15(19-20-16(11)13)10-6-7-23-9-10/h3-7,9H,2,8H2,1H3,(H,18,21)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt1 by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50209157 ((3-thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-...) Show SMILES CCOC(=O)Nc1cccc-2c1Cc1c-2n[nH]c1-c1ccsc1 Show InChI InChI=1S/C17H15N3O2S/c1-2-22-17(21)18-14-5-3-4-11-12(14)8-13-15(19-20-16(11)13)10-6-7-23-9-10/h3-7,9H,2,8H2,1H3,(H,18,21)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				Bioorg Med Chem Lett 17: 3136-40 (2007) Article DOI: 10.1016/j.bmcl.2007.03.031 BindingDB Entry DOI: 10.7270/Q2VD6Z3Q
					More data for this Ligand-Target Pair