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BDBM50213932 CHEMBL250474::[(R)-(+)-deoxytylophorinidine

SMILES: COc1ccc2c3C[C@H]4CCCN4Cc3c3cc(OC)c(O)cc3c2c1

InChI Key: InChIKey=DACRWRGHESRUQW-CYBMUJFWSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213932   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50213932
PNG
(CHEMBL250474 | [(R)-(+)-deoxytylophorinidine)
Show SMILES COc1ccc2c3C[C@H]4CCCN4Cc3c3cc(OC)c(O)cc3c2c1
Show InChI InChI=1S/C22H23NO3/c1-25-14-5-6-15-16-8-13-4-3-7-23(13)12-20(16)19-11-22(26-2)21(24)10-18(19)17(15)9-14/h5-6,9-11,13,24H,3-4,7-8,12H2,1-2H3/t13-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assay


Bioorg Med Chem Lett 17: 4338-42 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.021
BindingDB Entry DOI: 10.7270/Q2HD7VBW
More data for this
Ligand-Target Pair