BDBM50215009 CHEMBL251757::N-(2-aminophenyl)-4-(2-hydroxy-1,3-dioxo-1,3-bis(phenylamino)propan-2-yl)benzamide

SMILES: Nc1ccccc1NC(=O)c1ccc(cc1)C(O)(C(=O)Nc1ccccc1)C(=O)Nc1ccccc1

InChI Key: InChIKey=GPMIKDVJZRUNCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50215009 (CHEMBL251757 | N-(2-aminophenyl)-4-(2-hydroxy-1,3-...) Show SMILES Nc1ccccc1NC(=O)c1ccc(cc1)C(O)(C(=O)Nc1ccccc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C28H24N4O4/c29-23-13-7-8-14-24(23)32-25(33)19-15-17-20(18-16-19)28(36,26(34)30-21-9-3-1-4-10-21)27(35)31-22-11-5-2-6-12-22/h1-18,36H,29H2,(H,30,34)(H,31,35)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human HDAC1 expressed in domain of SMRT				Bioorg Med Chem Lett 17: 4619-24 (2007) Article DOI: 10.1016/j.bmcl.2007.05.080 BindingDB Entry DOI: 10.7270/Q2WH2PPV
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