BDBM50218046 (R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(4-methylpent-3-enyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)-2-phenylacetamide::CHEMBL250030
SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#7]-1-[#6]-[#6@H]-2-[#6@@H](-[#6]-1)-[#6@@H]-2-[#7]-[#6](=O)C([#8])([#6]-1-[#6]-[#6]-[#6]-[#6]-1)c1ccccc1
InChI Key: InChIKey=AEJIBUFVDPGRBC-SZJSPXDBSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M3 (RAT) | BDBM50218046 ((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(4-met...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular gland | Bioorg Med Chem Lett 17: 5256-60 (2007) Article DOI: 10.1016/j.bmcl.2007.06.081 BindingDB Entry DOI: 10.7270/Q27D2W0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50218046 ((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(4-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ranbaxy Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-methylscopolamine from muscarinic M2 receptor in rat heart | Bioorg Med Chem Lett 17: 5256-60 (2007) Article DOI: 10.1016/j.bmcl.2007.06.081 BindingDB Entry DOI: 10.7270/Q27D2W0F | |||||||||||
More data for this Ligand-Target Pair |