BDBM50223170 CHEMBL239655::N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]but-2-yn-1-amine methiodide

SMILES: Cc1cc(OCC#CC[N+](C)(C)C)no1

InChI Key: InChIKey=SHEUDFANHWXKDD-UHFFFAOYSA-N

Data: 5 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50223170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	682	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M4 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M3 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M5 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M1 receptor expressed in CHO cells				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Cavia porcellus)	BDBM50223170 (CHEMBL239655 | N,N-dimethyl-4-[(5-methylisoxazol-3...) Show SMILES Cc1cc(OCC#CC[N+](C)(C)C)no1 Show InChI InChI=1S/C11H17N2O2/c1-10-9-11(12-15-10)14-8-6-5-7-13(2,3)4/h9H,7-8H2,1-4H3/q+1	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	676	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity to muscarinic M3 receptor in guinea-pig ileum				Bioorg Med Chem 15: 7626-37 (2007) Article DOI: 10.1016/j.bmc.2007.09.003 BindingDB Entry DOI: 10.7270/Q29K4C27
					More data for this Ligand-Target Pair