BDBM50229244 CHEMBL70607

SMILES: CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1C(F)(F)F

InChI Key: InChIKey=IWFSPOYAFLPPQD-GHVJWSGMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50229244 (CHEMBL70607) Show SMILES CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1C(F)(F)F |c:12,t:9| Show InChI InChI=1S/C24H20ClF3N2O4S/c1-3-34-23(31)22-20(13-35(32,33)16-10-8-15(25)9-11-16)30-14(2)18(12-29)21(22)17-6-4-5-7-19(17)24(26,27)28/h4-11,21,31H,3,13H2,1-2H3/b23-22+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine				J Med Chem 34: 2248-60 (1991) BindingDB Entry DOI: 10.7270/Q27P91MK
					More data for this Ligand-Target Pair