Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50229244'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50229244 (CHEMBL70607) Show SMILES CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1C(F)(F)F |c:12,t:9| Show InChI InChI=1S/C24H20ClF3N2O4S/c1-3-34-23(31)22-20(13-35(32,33)16-10-8-15(25)9-11-16)30-14(2)18(12-29)21(22)17-6-4-5-7-19(17)24(26,27)28/h4-11,21,31H,3,13H2,1-2H3/b23-22+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine				J Med Chem 34: 2248-60 (1991) BindingDB Entry DOI: 10.7270/Q27P91MK
					More data for this Ligand-Target Pair