BDBM50231784 CHEMBL251067::[5-(4-Chlorophenyl)furan-2-yl-(4-dimethylaminopiperidin-1-yl)-methanone::[5-(4-chlorophenyl)furan-2-yl]-[4-(dimethylamino)piperidin-1-yl]methanone

SMILES: CN(C)C1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1

InChI Key: InChIKey=CEKBOFCQHHPDJK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50231784 (CHEMBL251067 | [5-(4-Chlorophenyl)furan-2-yl-(4-di...) Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H21ClN2O2/c1-20(2)15-9-11-21(12-10-15)18(22)17-8-7-16(23-17)13-3-5-14(19)6-4-13/h3-8,15H,9-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50231784 (CHEMBL251067 | [5-(4-Chlorophenyl)furan-2-yl-(4-di...) Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H21ClN2O2/c1-20(2)15-9-11-21(12-10-15)18(22)17-8-7-16(23-17)13-3-5-14(19)6-4-13/h3-8,15H,9-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay				Bioorg Med Chem 16: 6379-86 (2008) Article DOI: 10.1016/j.bmc.2008.05.003 BindingDB Entry DOI: 10.7270/Q2VH5NNT
					More data for this Ligand-Target Pair