BDBM50233972 CHEMBL4098509

SMILES: CCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1

InChI Key: InChIKey=YTWXKAWNLYIAPW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-2 (Homo sapiens (Human))	BDBM50233972 (CHEMBL4098509) Show SMILES CCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 Show InChI InChI=1S/C19H37N5/c1-5-6-7-8-9-10-11-12-13-20-18-16-17(2)22-19(23-18)21-14-15-24(3)4/h16H,5-15H2,1-4H3,(H2,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...				J Med Chem 60: 349-361 (2017) BindingDB Entry DOI: 10.7270/Q27M0B6T
					More data for this Ligand-Target Pair
Dynamin-2 (Homo sapiens (Human))	BDBM50233972 (CHEMBL4098509) Show SMILES CCCCCCCCCCNc1cc(C)nc(NCCN(C)C)n1 Show InChI InChI=1S/C19H37N5/c1-5-6-7-8-9-10-11-12-13-20-18-16-17(2)22-19(23-18)21-14-15-24(3)4/h16H,5-15H2,1-4H3,(H2,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...				J Med Chem 60: 349-361 (2017) BindingDB Entry DOI: 10.7270/Q27M0B6T
					More data for this Ligand-Target Pair