BDBM50240211 CHEMBL4104586

SMILES: CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(NC(=O)c3cccc(c3)-c3ccccn3)c2)CC1

InChI Key: InChIKey=PLAYYQDTNSRGEA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50240211 (CHEMBL4104586) Show SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(NC(=O)c3cccc(c3)-c3ccccn3)c2)CC1 Show InChI InChI=1S/C33H32F3N5O2/c1-22-9-12-27(20-30(22)39-32(43)24-7-5-6-23(18-24)29-8-3-4-13-37-29)38-31(42)25-10-11-26(28(19-25)33(34,35)36)21-41-16-14-40(2)15-17-41/h3-13,18-20H,14-17,21H2,1-2H3,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Integral BioSciences Pvt. Ltd Curated by ChEMBL					Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...				Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50240211 (CHEMBL4104586) Show SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(NC(=O)c3cccc(c3)-c3ccccn3)c2)CC1 Show InChI InChI=1S/C33H32F3N5O2/c1-22-9-12-27(20-30(22)39-32(43)24-7-5-6-23(18-24)29-8-3-4-13-37-29)38-31(42)25-10-11-26(28(19-25)33(34,35)36)21-41-16-14-40(2)15-17-41/h3-13,18-20H,14-17,21H2,1-2H3,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Integral BioSciences Pvt. Ltd Curated by ChEMBL					Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...				Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2
					More data for this Ligand-Target Pair