BDBM50240228 CHEMBL4060882
SMILES: CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cccc(c4)-c4cccnc4)c3)cc2C(F)(F)F)CC1
InChI Key: InChIKey=KBCISYCUHRRWQT-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM50240228 (CHEMBL4060882) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50240228 (CHEMBL4060882) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair |