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SMILES: Clc1ccc2OCCCCOc3ccnc4[nH]c(=O)n(-c1n2)c34

InChI Key: InChIKey=LPRLTDMLMUCBIR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240304   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C theta type


(Homo sapiens (Human))		BDBM50240304
PNG
(CHEMBL4099368)
Show SMILES Clc1ccc2OCCCCOc3ccnc4[nH]c(=O)n(-c1n2)c34
Show InChI InChI=1S/C15H13ClN4O3/c16-9-3-4-11-18-14(9)20-12-10(22-7-1-2-8-23-11)5-6-17-13(12)19-15(20)21/h3-6H,1-2,7-8H2,(H,17,19,21)
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n/an/a 14n/an/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL


Assay Description
Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...

Bioorg Med Chem Lett 27: 2497-2501 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.099
BindingDB Entry DOI: 10.7270/Q21G0PCZ
More data for this
Ligand-Target Pair