BDBM50243875 CHEMBL451118::cis-3-Amino-cyclobutyl(methyl)phosphinic acid

SMILES: CP(O)(O)C1=C[C@@H](N)C1

InChI Key: InChIKey=PLTLBLBWCQDIKR-SCSAIBSYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-C receptor (Homo sapiens (Human))	BDBM50243875 (CHEMBL451118 | cis-3-Amino-cyclobutyl(methyl)phosp...) Show SMILES CP(O)(O)C1=C[C@@H](N)C1 |r,t:4| Show InChI InChI=1S/C5H12NO2P/c1-9(7,8)5-2-4(6)3-5/h2,4,7-9H,3,6H2,1H3/t4-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
					More data for this Ligand-Target Pair