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BDBM50251936 2-Ethylsulfanyl-4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridine::CHEMBL516761

SMILES: CCSc1cc(ccn1)-c1nc(SC)[nH]c1-c1ccc(F)cc1

InChI Key: InChIKey=YDZIRFOTAHFWMI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50251936
PNG
(2-Ethylsulfanyl-4-[4-(4-fluoro-phenyl)-2-methylsul...)
Show SMILES CCSc1cc(ccn1)-c1nc(SC)[nH]c1-c1ccc(F)cc1
Show InChI InChI=1S/C17H16FN3S2/c1-3-23-14-10-12(8-9-19-14)16-15(20-17(21-16)22-2)11-4-6-13(18)7-5-11/h4-10H,3H2,1-2H3,(H,20,21)
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MMDB

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Article
PubMed
n/an/a 87n/an/an/an/an/an/a



Eberhard-Karls-University Tuebingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


J Med Chem 51: 4122-49 (2008)


Article DOI: 10.1021/jm701529q
BindingDB Entry DOI: 10.7270/Q2W37X67
More data for this
Ligand-Target Pair