BDBM50251999 2-(3-hydroxy-2-(3-phenylpropanamido)-2,3-dihydrothiazol-4-yl)acetic acid::CHEMBL481168

SMILES: OC(=O)Cc1csc(=NC(=O)CCc2ccccc2)n1O

InChI Key: InChIKey=XJRQAFGUSSLTJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50251999 (2-(3-hydroxy-2-(3-phenylpropanamido)-2,3-dihydroth...) Show SMILES OC(=O)Cc1csc(=NC(=O)CCc2ccccc2)n1O |w:8.8| Show InChI InChI=1S/C14H14N2O4S/c17-12(7-6-10-4-2-1-3-5-10)15-14-16(20)11(9-21-14)8-13(18)19/h1-5,9,20H,6-8H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assay				Bioorg Med Chem Lett 18: 3925-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.031 BindingDB Entry DOI: 10.7270/Q2XW4JM5
					More data for this Ligand-Target Pair