BDBM50253153 CHEMBL495330::N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)benzamide

SMILES: Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1

InChI Key: InChIKey=LQXUFIFTFVOCHC-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50253153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of Lck (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of JNK3 (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of JNK2 (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50253153 (CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1 Show InChI InChI=1S/C25H21N3O/c1-16-7-8-19(25(29)27-21-10-11-21)14-23(16)18-9-12-22-20(13-18)15-26-28-24(22)17-5-3-2-4-6-17/h2-9,12-15,21H,10-11H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of cKit (unknown origin)				J Med Chem 51: 6271-9 (2008) Article DOI: 10.1021/jm8005417 BindingDB Entry DOI: 10.7270/Q2WH2PTN
					More data for this Ligand-Target Pair