BindingDB PrimarySearch

BDBM50254790 (S)-Norfluoxetine::CHEMBL465123::NORFLUOXETINE

SMILES: NCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=WIQRCHMSJFFONW-HNNXBMFYSA-N

Data: 37 KI 5 IC50 1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50254790
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Eur J Pharmacol 340: 249-58 (1997) Article DOI: 10.1016/s0014-2999(97)01393-9 BindingDB Entry DOI: 10.7270/Q2V69H3D
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turku Curated by PDSP K_i Database									Psychopharmacology (Berl) 126: 234-40 (1996) Article DOI: 10.1007/bf02246453 BindingDB Entry DOI: 10.7270/Q2BP0192
University of Turku Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boots Pharmaceuticals Curated by PDSP K_i Database									Neuropharmacology 32: 737-43 (1993) Article DOI: 10.1016/0028-3908(93)90181-2 BindingDB Entry DOI: 10.7270/Q22J69D4
Boots Pharmaceuticals Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	13.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boots Pharmaceuticals Curated by PDSP K_i Database									Neuropharmacology 32: 737-43 (1993) Article DOI: 10.1016/0028-3908(93)90181-2 BindingDB Entry DOI: 10.7270/Q22J69D4
Boots Pharmaceuticals Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	30.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 (1997) Article DOI: 10.1016/s0028-3908(97)00049-x BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	91.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 (1997) Article DOI: 10.1016/s0028-3908(97)00049-x BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 (1997) Article DOI: 10.1016/s0028-3908(97)00049-x BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turku Curated by PDSP K_i Database									Psychopharmacology (Berl) 126: 234-40 (1996) Article DOI: 10.1007/bf02246453 BindingDB Entry DOI: 10.7270/Q2BP0192
University of Turku Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 (1997) Article DOI: 10.1016/s0028-3908(97)00049-x BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Eur J Pharmacol 340: 249-58 (1997) Article DOI: 10.1016/s0014-2999(97)01393-9 BindingDB Entry DOI: 10.7270/Q2V69H3D
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	638	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP K_i Database									Biochem Pharmacol 45: 2352-4 (1993) Article DOI: 10.1016/0006-2952(93)90211-e BindingDB Entry DOI: 10.7270/Q2F76B2C
Mayo Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turku Curated by PDSP K_i Database									Psychopharmacology (Berl) 126: 234-40 (1996) Article DOI: 10.1007/bf02246453 BindingDB Entry DOI: 10.7270/Q2BP0192
University of Turku Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP K_i Database									Biochem Pharmacol 45: 2352-4 (1993) Article DOI: 10.1016/0006-2952(93)90211-e BindingDB Entry DOI: 10.7270/Q2F76B2C
Mayo Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Eur J Pharmacol 340: 249-58 (1997) Article DOI: 10.1016/s0014-2999(97)01393-9 BindingDB Entry DOI: 10.7270/Q2V69H3D
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP K_i Database									Biochem Pharmacol 45: 2352-4 (1993) Article DOI: 10.1016/0006-2952(93)90211-e BindingDB Entry DOI: 10.7270/Q2F76B2C
Mayo Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP K_i Database									Biochem Pharmacol 45: 2352-4 (1993) Article DOI: 10.1016/0006-2952(93)90211-e BindingDB Entry DOI: 10.7270/Q2F76B2C
Mayo Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP K_i Database									Biochem Pharmacol 45: 2352-4 (1993) Article DOI: 10.1016/0006-2952(93)90211-e BindingDB Entry DOI: 10.7270/Q2F76B2C
Mayo Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Norepinephrine transporter (RAT)	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 283: 1305-22 (1997) BindingDB Entry DOI: 10.7270/Q25Q4TMX
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 (1997) Article DOI: 10.1016/s0028-3908(97)00049-x BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TCG Lifesciences Ltd. Curated by ChEMBL					Assay Description Inhibition of human ERG				Eur J Med Chem 46: 618-30 (2011) Article DOI: 10.1016/j.ejmech.2010.11.042 BindingDB Entry DOI: 10.7270/Q2WQ052W
TCG Lifesciences Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily C member 1 (Rattus norvegicus)	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of rat voltage-gated K channel 3.1 expressed in CHO cells by patch clamp assay				J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Twik-RElated Potassium (K+) channel 1 (TREK1) (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	7.3	22
Korea Institute of Science and Technology					Assay Description The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...				Chem Biol Drug Des 88: 807-819 (2016) Article DOI: 10.1111/cbdd.12810 BindingDB Entry DOI: 10.7270/Q2S181B1
Korea Institute of Science and Technology					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50254790 ((S)-Norfluoxetine \| CHEMBL465123 \| NORFLUOXETINE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cells				Bioorg Med Chem 17: 337-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.065 BindingDB Entry DOI: 10.7270/Q2WQ04Q0
Human BioMolecular Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair