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BDBM50255917 CHEMBL480923::N-(2-aminophenyl)-4-((3-(pyridin-3-yl)phenylamino)methyl)benzamide

SMILES: Nc1ccccc1NC(=O)c1ccc(CNc2cccc(c2)-c2cccnc2)cc1

InChI Key: InChIKey=LKAOVJNDDTXFSU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255917   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))
BDBM50255917
PNG
(CHEMBL480923 | N-(2-aminophenyl)-4-((3-(pyridin-3-...)
Show SMILES Nc1ccccc1NC(=O)c1ccc(CNc2cccc(c2)-c2cccnc2)cc1
Show InChI InChI=1S/C25H22N4O/c26-23-8-1-2-9-24(23)29-25(30)19-12-10-18(11-13-19)16-28-22-7-3-5-20(15-22)21-6-4-14-27-17-21/h1-15,17,28H,16,26H2,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant HDAC1


Bioorg Med Chem Lett 19: 644-9 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.048
BindingDB Entry DOI: 10.7270/Q2PN95J1
More data for this
Ligand-Target Pair