null
SMILES: CC(C)CC[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O
InChI Key: InChIKey=YCAVDJDBHPHXEP-QHCPKHFHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen phosphorylase, liver form (Homo sapiens (Human)) | BDBM50256573 ((S)-2-(3-(3-mesitylureido)-2-naphthamido)-5-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 452 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of liver glycogen phosphorylase A in human HepG2 cells assessed as inhibition of forskolin-induced glucogenolysis | Bioorg Med Chem Lett 19: 981-5 (2009) Article DOI: 10.1016/j.bmcl.2008.11.084 BindingDB Entry DOI: 10.7270/Q2319VRH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50256573 ((S)-2-(3-(3-mesitylureido)-2-naphthamido)-5-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2C9 (unknown origin) | Bioorg Med Chem Lett 19: 981-5 (2009) Article DOI: 10.1016/j.bmcl.2008.11.084 BindingDB Entry DOI: 10.7270/Q2319VRH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen phosphorylase, liver form (Homo sapiens (Human)) | BDBM50256573 ((S)-2-(3-(3-mesitylureido)-2-naphthamido)-5-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assay | Bioorg Med Chem Lett 19: 981-5 (2009) Article DOI: 10.1016/j.bmcl.2008.11.084 BindingDB Entry DOI: 10.7270/Q2319VRH | |||||||||||
More data for this Ligand-Target Pair |