BDBM50260188 CHEMBL4069509

SMILES: COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl

InChI Key: InChIKey=QBOPLHQHJDUIPC-BQYQJAHWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50260188 (CHEMBL4069509) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl Show InChI InChI=1S/C28H37Cl2N7O4/c1-17(2)32-27-31-15-18-16-36(25-23(29)20(40-5)14-21(41-6)24(25)30)28(39)37(26(18)33-27)19-9-12-35(13-10-19)22(38)8-7-11-34(3)4/h7-8,14-15,17,19H,9-13,16H2,1-6H3,(H,31,32,33)/b8-7+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged FGFR4 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50260188 (CHEMBL4069509) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl Show InChI InChI=1S/C28H37Cl2N7O4/c1-17(2)32-27-31-15-18-16-36(25-23(29)20(40-5)14-21(41-6)24(25)30)28(39)37(26(18)33-27)19-9-12-35(13-10-19)22(38)8-7-11-34(3)4/h7-8,14-15,17,19H,9-13,16H2,1-6H3,(H,31,32,33)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50260188 (CHEMBL4069509) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl Show InChI InChI=1S/C28H37Cl2N7O4/c1-17(2)32-27-31-15-18-16-36(25-23(29)20(40-5)14-21(41-6)24(25)30)28(39)37(26(18)33-27)19-9-12-35(13-10-19)22(38)8-7-11-34(3)4/h7-8,14-15,17,19H,9-13,16H2,1-6H3,(H,31,32,33)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50260188 (CHEMBL4069509) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC(C)C)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl Show InChI InChI=1S/C28H37Cl2N7O4/c1-17(2)32-27-31-15-18-16-36(25-23(29)20(40-5)14-21(41-6)24(25)30)28(39)37(26(18)33-27)19-9-12-35(13-10-19)22(38)8-7-11-34(3)4/h7-8,14-15,17,19H,9-13,16H2,1-6H3,(H,31,32,33)/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged FGFR3 cytoplasmic domain (399 to 806 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair