null
SMILES: ONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=LJLSVOSAAMOXNZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Matrilysin (Homo sapiens (Human)) | BDBM50260799 (CHEMBL497962 | N-hydroxy-2,3-bis(3-(trifluoromethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 602 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP7 | Bioorg Med Chem Lett 18: 3333-7 (2008) Article DOI: 10.1016/j.bmcl.2008.04.035 BindingDB Entry DOI: 10.7270/Q2SX6D1R | |||||||||||
More data for this Ligand-Target Pair |