BDBM50261856 CHEMBL4071926

SMILES: [#6]\[#6](-[#6])=[#6]\c1c(Cl)c2c(Cl)cc(nc2n1-[#6]-1-[#6]-[#6]-[#6]-[#7]-[#6]-1)-[#6](-[#7])=O

InChI Key: InChIKey=WVOATLASLUXFNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50261856 (CHEMBL4071926) Show SMILES [#6]\[#6](-[#6])=[#6]\c1c(Cl)c2c(Cl)cc(nc2n1-[#6]-1-[#6]-[#6]-[#6]-[#7]-[#6]-1)-[#6](-[#7])=O Show InChI InChI=1S/C17H20Cl2N4O/c1-9(2)6-13-15(19)14-11(18)7-12(16(20)24)22-17(14)23(13)10-4-3-5-21-8-10/h6-7,10,21H,3-5,8H2,1-2H3,(H2,20,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis H37RV InhA				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50261856 (CHEMBL4071926) Show SMILES [#6]\[#6](-[#6])=[#6]\c1c(Cl)c2c(Cl)cc(nc2n1-[#6]-1-[#6]-[#6]-[#6]-[#7]-[#6]-1)-[#6](-[#7])=O Show InChI InChI=1S/C17H20Cl2N4O/c1-9(2)6-13-15(19)14-11(18)7-12(16(20)24)22-17(14)23(13)10-4-3-5-21-8-10/h6-7,10,21H,3-5,8H2,1-2H3,(H2,20,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair