BDBM50262587 3-[4-({3-[(2R,5R)-2,5-Dimethyl-1-pyrrolidinyl]propyl}oxy)phenyl]-4(3H)-quinazolinone::CHEMBL443958

SMILES: C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=SJGNWKLQQZVTKR-QZTJIDSGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50262587 (3-[4-({3-[(2R,5R)-2,5-Dimethyl-1-pyrrolidinyl]prop...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O |r| Show InChI InChI=1S/C24H29N3O2/c1-17-9-10-18(2)26(17)15-6-16-29-21-13-11-20(12-14-21)27-19(3)25-23-8-5-4-7-22(23)24(27)28/h4-5,7-8,11-14,17-18H,6,9-10,15-16H2,1-3H3/t17-,18-/m1/s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells				J Med Chem 51: 4780-9 (2008) Article DOI: 10.1021/jm8003834 BindingDB Entry DOI: 10.7270/Q2FQ9WFW
					More data for this Ligand-Target Pair