BDBM50263411 1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL478034

SMILES: [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=RCRAYIPXTHUIJR-UHFFFAOYSA-N

Data: 1 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M5 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M1 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of dopamine D2 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M3 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M4 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50263411 (1-[1'-(2-Nitro-benzyl)-[1,4']bipiperidinyl-4-yl]-1...) Show SMILES [O-][N+](=O)c1ccccc1CN1CCC(CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O3/c30-24-25-21-6-2-4-8-23(21)28(24)20-11-15-27(16-12-20)19-9-13-26(14-10-19)17-18-5-1-3-7-22(18)29(31)32/h1-8,19-20H,9-17H2,(H,25,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at muscarinic M2 receptor (unknown origin)				Bioorg Med Chem Lett 18: 5439-42 (2008) Article DOI: 10.1016/j.bmcl.2008.09.023 BindingDB Entry DOI: 10.7270/Q2708198
					More data for this Ligand-Target Pair