BDBM50264635 CHEMBL490013::N-(7,9-Difluoro-5-N-methyl-10H-indolo[3,2-b]quinolin-5-ium)-N,N-diethyl-propane-1,3-diamine Iodide

SMILES: CCN(CC)CCCNc1c2[nH+]c3c(F)cc(F)cc3c2n(C)c2ccccc12

InChI Key: InChIKey=LXNAENTZLBVGAE-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50264635 (CHEMBL490013 | N-(7,9-Difluoro-5-N-methyl-10H-indo...) Show SMILES CCN(CC)CCCNc1c2[nH+]c3c(F)cc(F)cc3c2n(C)c2ccccc12 Show InChI InChI=1S/C23H26F2N4/c1-4-29(5-2)12-8-11-26-21-16-9-6-7-10-19(16)28(3)23-17-13-15(24)14-18(25)20(17)27-22(21)23/h6-7,9-10,13-14,26H,4-5,8,11-12H2,1-3H3/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of telomerase in human MCF7 cells by cell-free telomerase repeat amplification protocol assay				J Med Chem 51: 6381-92 (2008) Article DOI: 10.1021/jm800497p BindingDB Entry DOI: 10.7270/Q2319VQ2
					More data for this Ligand-Target Pair