BDBM50264822 CHEMBL4091946

SMILES: OC(=O)c1ccc2c(c1)C(=O)OC21CCN(CC1)c1ccc(cn1)-c1nc2cc(ccc2[nH]1)C(F)(F)F

InChI Key: InChIKey=YYEOGOCGDPAYFM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50264822 (CHEMBL4091946) Show SMILES OC(=O)c1ccc2c(c1)C(=O)OC21CCN(CC1)c1ccc(cn1)-c1nc2cc(ccc2[nH]1)C(F)(F)F Show InChI InChI=1S/C26H19F3N4O4/c27-26(28,29)16-3-5-19-20(12-16)32-22(31-19)15-2-6-21(30-13-15)33-9-7-25(8-10-33)18-4-1-14(23(34)35)11-17(18)24(36)37-25/h1-6,11-13H,7-10H2,(H,31,32)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co., Inc. Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in yeast membrane fraction assessed as inhibition of triglyceride formation using diolein/oleoyl-CoA as substrate...				J Med Chem 60: 3594-3605 (2017) Article DOI: 10.1021/acs.jmedchem.6b01543 BindingDB Entry DOI: 10.7270/Q290267S
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50264822 (CHEMBL4091946) Show SMILES OC(=O)c1ccc2c(c1)C(=O)OC21CCN(CC1)c1ccc(cn1)-c1nc2cc(ccc2[nH]1)C(F)(F)F Show InChI InChI=1S/C26H19F3N4O4/c27-26(28,29)16-3-5-19-20(12-16)32-22(31-19)15-2-6-21(30-13-15)33-9-7-25(8-10-33)18-4-1-14(23(34)35)11-17(18)24(36)37-25/h1-6,11-13H,7-10H2,(H,31,32)(H,34,35)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co., Inc. Curated by ChEMBL					Assay Description Inhibition of MK499 binding to human ERG				J Med Chem 60: 3594-3605 (2017) Article DOI: 10.1021/acs.jmedchem.6b01543 BindingDB Entry DOI: 10.7270/Q290267S
					More data for this Ligand-Target Pair