BDBM50267841 (R)-5-Oxo-5-4-[(1,3-thiazole-2-amino)sulfonyl]phenylamino-4-[(3,4,5-trimethoxybenzamido)amino]pentanoic acid::CHEMBL486063

SMILES: COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1

InChI Key: InChIKey=ZANUNWQWTQAZRE-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50267841 ((R)-5-Oxo-5-4-[(1,3-thiazole-2-amino)sulfonyl]phen...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C24H26N4O9S2/c1-35-18-12-14(13-19(36-2)21(18)37-3)22(31)27-17(8-9-20(29)30)23(32)26-15-4-6-16(7-5-15)39(33,34)28-24-25-10-11-38-24/h4-7,10-13,17H,8-9H2,1-3H3,(H,25,28)(H,26,32)(H,27,31)(H,29,30)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 by spectrophotometry				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50267841 ((R)-5-Oxo-5-4-[(1,3-thiazole-2-amino)sulfonyl]phen...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 |r| Show InChI InChI=1S/C24H26N4O9S2/c1-35-18-12-14(13-19(36-2)21(18)37-3)22(31)27-17(8-9-20(29)30)23(32)26-15-4-6-16(7-5-15)39(33,34)28-24-25-10-11-38-24/h4-7,10-13,17H,8-9H2,1-3H3,(H,25,28)(H,26,32)(H,27,31)(H,29,30)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsome aminopeptidase N by UV-visible spectrophotometer				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair