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BDBM50269614 2-Methyl-beta-carboline-2-ium iodide::2-methyl-2H-pyrido[3,4-b]indole hydroiodide::2-methylnorharmane iodide::CHEMBL455600

SMILES: C[n+]1ccc2c(c1)[nH]c1ccccc21

InChI Key: InChIKey=UDHBHTHWWOQPBW-UHFFFAOYSA-O

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269614   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50269614
PNG
(2-Methyl-beta-carboline-2-ium iodide | 2-methyl-2H...)
Show SMILES C[n+]1ccc2c(c1)[nH]c1ccccc21
Show InChI InChI=1S/C12H10N2/c1-14-7-6-10-9-4-2-3-5-11(9)13-12(10)8-14/h2-8H,1H3/p+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.12E+4n/an/an/an/an/an/a



University of Zürich

Curated by ChEMBL


Assay Description
Inhibition of horse serum BChE by Ellman's reaction


J Nat Prod 68: 1793-5 (2005)


Article DOI: 10.1021/np050312l
BindingDB Entry DOI: 10.7270/Q2K9378M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50269614
PNG
(2-Methyl-beta-carboline-2-ium iodide | 2-methyl-2H...)
Show SMILES C[n+]1ccc2c(c1)[nH]c1ccccc21
Show InChI InChI=1S/C12H10N2/c1-14-7-6-10-9-4-2-3-5-11(9)13-12(10)8-14/h2-8H,1H3/p+1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Friedrich-Schiller-Universitat Jena

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE by modified Ellman's method


J Med Chem 53: 3611-7 (2010)


Article DOI: 10.1021/jm1000024
BindingDB Entry DOI: 10.7270/Q2SJ1KS0
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50269614
PNG
(2-Methyl-beta-carboline-2-ium iodide | 2-methyl-2H...)
Show SMILES C[n+]1ccc2c(c1)[nH]c1ccccc21
Show InChI InChI=1S/C12H10N2/c1-14-7-6-10-9-4-2-3-5-11(9)13-12(10)8-14/h2-8H,1H3/p+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Friedrich-Schiller-Universitat Jena

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE by modified Ellman's method


J Med Chem 53: 3611-7 (2010)


Article DOI: 10.1021/jm1000024
BindingDB Entry DOI: 10.7270/Q2SJ1KS0
More data for this
Ligand-Target Pair