BDBM50269645 3,4-dihydroxyxanthone::CHEMBL446323::US9114126, MB2

SMILES: Oc1ccc2c(oc3ccccc3c2=O)c1O

InChI Key: InChIKey=YFVCSEXMOBEPQB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50269645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Na/K-ATPase (Sus scrofa (Pig))	BDBM50269645 (3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...) Show SMILES Oc1ccc2c(oc3ccccc3c2=O)c1O Show InChI InChI=1S/C13H8O4/c14-9-6-5-8-11(15)7-3-1-2-4-10(7)17-13(8)12(9)16/h1-6,14,16H	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	37
THE UNIVERSITY OF TOLEDO US Patent					Assay Description The purified Na/K-ATPase was prepared from pig kidney. The specific activities of Na/K-ATPase of various kidney preparations were in the range of 900...				US Patent US9114126 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XFQ
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50269645 (3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...) Show SMILES Oc1ccc2c(oc3ccccc3c2=O)c1O Show InChI InChI=1S/C13H8O4/c14-9-6-5-8-11(15)7-3-1-2-4-10(7)17-13(8)12(9)16/h1-6,14,16H	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	5.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50269645 (3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...) Show SMILES Oc1ccc2c(oc3ccccc3c2=O)c1O Show InChI InChI=1S/C13H8O4/c14-9-6-5-8-11(15)7-3-1-2-4-10(7)17-13(8)12(9)16/h1-6,14,16H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human COX2 expressed in sf9 cells				J Nat Prod 68: 1514-8 (2005) Article DOI: 10.1021/np0502342 BindingDB Entry DOI: 10.7270/Q23778HN
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50269645 (3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...) Show SMILES Oc1ccc2c(oc3ccccc3c2=O)c1O Show InChI InChI=1S/C13H8O4/c14-9-6-5-8-11(15)7-3-1-2-4-10(7)17-13(8)12(9)16/h1-6,14,16H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human COX1 expressed in sf9 cells				J Nat Prod 68: 1514-8 (2005) Article DOI: 10.1021/np0502342 BindingDB Entry DOI: 10.7270/Q23778HN
					More data for this Ligand-Target Pair