| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium-transporting ATPase alpha chain 1 |
|---|
| Ligand | BDBM50269645 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | High Throughput Screening Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | >100000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Xie, Z; Shapiro, JI; Si, S; Zhang, Z Na/K-ATPase ligands, ouabain antagonists, assays and uses thereof US Patent US9114126 Publication Date 8/25/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium-transporting ATPase alpha chain 1 |
|---|
| Name: | Potassium-transporting ATPase alpha chain 1 |
|---|
| Synonyms: | ATP4A | ATP4A_PIG | Gastric H(+)/K(+) ATPase subunit alpha | H+/K+-ATPase | Na/K-ATPase | Potassium-transporting ATPase | Potassium-transporting ATPase alpha chain 1 | Proton pump |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 114279.23 |
|---|
| Organism: | Sus scrofa (Pig) |
|---|
| Description: | P19156 |
|---|
| Residue: | 1034 |
|---|
| Sequence: | MGKAENYELYQVELGPGPSGDMAAKMSKKKAGRGGGKRKEKLENMKKEMEINDHQLSVAE
LEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAI
CLIAFAIQASEGDLTTDDNLYLALALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQAT
VIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILQAQGRKVDNSSLTGESEPQTRSPE
CTHESPLETRNIAFFSTMCLEGTAQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEH
FVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKR
LASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHSADTTEDQSGQT
FDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGY
RERFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHVLVMKGAPERVLERCSSILIKGQELPL
DEQWREAFQTAYLSLGGLGERVLGFCQLYLSEKDYPPGYAFDVEAMNFPTSGLSFAGLVS
MIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRV
PVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGA
IVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFD
NLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESD
IMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRPQW
ENHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSAFQQGFF
RNRILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGV
RCCPGSWWDQELYY
|
|
|
|---|
| BDBM50269645 |
|---|
| n/a |
|---|
| Name | BDBM50269645 |
|---|
| Synonyms: | 3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, MB2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H8O4 |
|---|
| Mol. Mass. | 228.2002 |
|---|
| SMILES | Oc1ccc2c(oc3ccccc3c2=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
