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BDBM50277120 CHEMBL4161645

SMILES: OCc1ccc(COc2coc3cccc(CC4CCCCC4)c3c2=O)cc1

InChI Key: InChIKey=GUKJFQMQAPKSAS-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277120   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-5


(Mus musculus)		BDBM50277120
PNG
(CHEMBL4161645)
Show SMILES OCc1ccc(COc2coc3cccc(CC4CCCCC4)c3c2=O)cc1
Show InChI InChI=1S/C24H26O4/c25-14-18-9-11-19(12-10-18)15-27-22-16-28-21-8-4-7-20(23(21)24(22)26)13-17-5-2-1-3-6-17/h4,7-12,16-17,25H,1-3,5-6,13-15H2
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PC cid
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Article
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n/an/a 1.10E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to control

Eur J Med Chem 139: 290-304 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.069
BindingDB Entry DOI: 10.7270/Q2B27XSJ
More data for this
Ligand-Target Pair