BDBM50279453 1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(3-(4-methylpiperazin-1-yl)propyl)imidazolidine-2,4-dione::CHEMBL487756

SMILES: CCOc1ccc2OCCC(=Nn3cc(O)n(CCCN4CCN(C)CC4)c3=O)c2c1

InChI Key: InChIKey=AHUIVEBFZQUDEQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Cavia porcellus)	BDBM50279453 (1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...) Show SMILES CCOc1ccc2OCCC(=Nn3cc(O)n(CCCN4CCN(C)CC4)c3=O)c2c1 |w:11.11| Show InChI InChI=1S/C22H31N5O4/c1-3-30-17-5-6-20-18(15-17)19(7-14-31-20)23-27-16-21(28)26(22(27)29)9-4-8-25-12-10-24(2)11-13-25/h5-6,15-16,28H,3-4,7-14H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50279453 (1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...) Show SMILES CCOc1ccc2OCCC(=Nn3cc(O)n(CCCN4CCN(C)CC4)c3=O)c2c1 |w:11.11| Show InChI InChI=1S/C22H31N5O4/c1-3-30-17-5-6-20-18(15-17)19(7-14-31-20)23-27-16-21(28)26(22(27)29)9-4-8-25-12-10-24(2)11-13-25/h5-6,15-16,28H,3-4,7-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair