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SMILES: Fc1cccnc1\C=N\NC(=S)SCC(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=INXLSWZOELUKTR-GZIVZEMBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystathionine gamma-lyase


(Homo sapiens (Human))		BDBM50280012
PNG
(CHEMBL4174491)
Show SMILES Fc1cccnc1\C=N\NC(=S)SCC(=O)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C16H12F4N4OS2/c17-12-2-1-7-21-13(12)8-22-24-15(26)27-9-14(25)23-11-5-3-10(4-6-11)16(18,19)20/h1-8H,9H2,(H,23,25)(H,24,26)/b22-8+
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Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...

ACS Med Chem Lett 8: 1241-1245 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00313
BindingDB Entry DOI: 10.7270/Q2N300GT
More data for this
Ligand-Target Pair