BDBM50280031 (6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol::CHEMBL421040
SMILES: OC1CCN2C[C@H](O)[C@@H](O)[C@H](O)C12
InChI Key: InChIKey=JDVVGAQPNNXQDW-SHIRPBDBSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280031 ((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 15 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280031 ((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 900 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on Asp. Wentii beta Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280031 ((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on almonds beta Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280031 ((6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | >1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair |