BDBM50283962 (S)-1-Benzyl-3,5-bis-(1H-indol-3-ylmethyl)-piperidin-4-one::CHEMBL347058

SMILES: O=C1C(Cc2c[nH]c3ccccc23)CN(Cc2ccccc2)C[C@@H]1Cc1c[nH]c2ccccc12

InChI Key: InChIKey=RYSWOVLQLJFYGU-SKCDSABHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50283962 ((S)-1-Benzyl-3,5-bis-(1H-indol-3-ylmethyl)-piperid...) Show SMILES O=C1C(Cc2c[nH]c3ccccc23)CN(Cc2ccccc2)C[C@@H]1Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C30H29N3O/c34-30-24(14-22-16-31-28-12-6-4-10-26(22)28)19-33(18-21-8-2-1-3-9-21)20-25(30)15-23-17-32-29-13-7-5-11-27(23)29/h1-13,16-17,24-25,31-32H,14-15,18-20H2/t24-,25?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards CCK-A receptor in rat pancreas using [125I]-Bolton-Hunter CCK-8 as radioligand; Value ranges from 3.5-4.6 uM				Bioorg Med Chem Lett 4: 525-530 (1994) Article DOI: 10.1016/0960-894X(94)80030-8 BindingDB Entry DOI: 10.7270/Q2BV7GKD
					More data for this Ligand-Target Pair