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SMILES: CC(CNCCOc1ccc(\C=C\c2ccccc2)cc1)c1ccccc1

InChI Key: InChIKey=WNJQYWRTNXZZRC-OUKQBFOZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288129   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Squalene synthase


(Rattus norvegicus)		BDBM50288129
PNG
((2-Phenyl-propyl)-{2-[4-((E)-styryl)-phenoxy]-ethy...)
Show SMILES CC(CNCCOc1ccc(\C=C\c2ccccc2)cc1)c1ccccc1
Show InChI InChI=1S/C25H27NO/c1-21(24-10-6-3-7-11-24)20-26-18-19-27-25-16-14-23(15-17-25)13-12-22-8-4-2-5-9-22/h2-17,21,26H,18-20H2,1H3/b13-12+
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n/an/a 9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay

Bioorg Med Chem Lett 6: 2491-2494 (1996)


Article DOI: 10.1016/0960-894X(96)00470-2
BindingDB Entry DOI: 10.7270/Q21V5DZZ
More data for this
Ligand-Target Pair