BDBM50289605 4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-yl)-pyrimidine::CHEMBL42061

SMILES: CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1

InChI Key: InChIKey=AKMGJJTVIPHEOZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289605 (4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1 Show InChI InChI=1S/C17H18N4O2/c1-20-5-7-21(8-6-20)17-18-14(13-4-10-22-12-13)11-15(19-17)16-3-2-9-23-16/h2-4,9-12H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50289605 (4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1 Show InChI InChI=1S/C17H18N4O2/c1-20-5-7-21(8-6-20)17-18-14(13-4-10-22-12-13)11-15(19-17)16-3-2-9-23-16/h2-4,9-12H,5-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat brain hippocampus				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair