BDBM50289934 3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid methyl ester::CHEMBL63169

SMILES: COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl

InChI Key: InChIKey=CGCWFYMUPJAHOG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50289934 (3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...) Show SMILES COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl Show InChI InChI=1S/C10H9ClN2O5S2/c1-5-7(11)9(18-12-5)13-20(15,16)6-3-4-19-8(6)10(14)17-2/h3-4,13H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETB receptor				Bioorg Med Chem Lett 7: 2093-2098 (1997) Article DOI: 10.1016/S0960-894X(97)00367-3 BindingDB Entry DOI: 10.7270/Q2WH2PZF
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50289934 (3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...) Show SMILES COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl Show InChI InChI=1S/C10H9ClN2O5S2/c1-5-7(11)9(18-12-5)13-20(15,16)6-3-4-19-8(6)10(14)17-2/h3-4,13H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETA receptor				Bioorg Med Chem Lett 7: 2093-2098 (1997) Article DOI: 10.1016/S0960-894X(97)00367-3 BindingDB Entry DOI: 10.7270/Q2WH2PZF
					More data for this Ligand-Target Pair