BDBM50291489 3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173977

SMILES: Cc1noc(NS(=O)(=O)c2sccc2CCc2c(C)cc(C)cc2C)c1Br

InChI Key: InChIKey=UICXKCWFYWPAOT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50291489 (3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-s...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2c(C)cc(C)cc2C)c1Br Show InChI InChI=1S/C19H21BrN2O3S2/c1-11-9-12(2)16(13(3)10-11)6-5-15-7-8-26-19(15)27(23,24)22-18-17(20)14(4)21-25-18/h7-10,22H,5-6H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50291489 (3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-s...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2c(C)cc(C)cc2C)c1Br Show InChI InChI=1S/C19H21BrN2O3S2/c1-11-9-12(2)16(13(3)10-11)6-5-15-7-8-26-19(15)27(23,24)22-18-17(20)14(4)21-25-18/h7-10,22H,5-6H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair