BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50291489'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1 receptor


(Homo sapiens (Human))		BDBM50291489
PNG
(3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-s...)
Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2c(C)cc(C)cc2C)c1Br
Show InChI InChI=1S/C19H21BrN2O3S2/c1-11-9-12(2)16(13(3)10-11)6-5-15-7-8-26-19(15)27(23,24)22-18-17(20)14(4)21-25-18/h7-10,22H,5-6H2,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 58n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assay

Bioorg Med Chem Lett 7: 939-944 (1997)


Article DOI: 10.1016/S0960-894X(97)00133-9
BindingDB Entry DOI: 10.7270/Q2959HKC
More data for this
Ligand-Target Pair