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BDBM50295925 (E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol::CHEMBL569136::Magreth-4

SMILES: C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O

InChI Key: InChIKey=MHZPQXNOHIORFI-GQCTYLIASA-N

Data: 2 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50295925   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50295925
PNG
((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Show SMILES C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
Show InChI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+
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UniChem
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1.76E+3n/an/an/an/an/an/an/an/a



University of Bern



Assay Description
Binding assay with hCB1 and hCB2 receptors.


Chem Biol 18: 1053-64 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.012
BindingDB Entry DOI: 10.7270/Q27W69PQ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50295925
PNG
((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Show SMILES C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
Show InChI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+
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>5.00E+3n/an/an/an/an/an/an/an/a



University of Bern



Assay Description
Binding assay with hCB1 and hCB2 receptors.


Chem Biol 18: 1053-64 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.012
BindingDB Entry DOI: 10.7270/Q27W69PQ
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50295925
PNG
((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Show SMILES C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
Show InChI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+
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n/an/a 600n/an/an/an/an/an/a



Karl-Franzens-Universit£t Graz

Curated by ChEMBL


Assay Description
Inhibition of COX1 in ram seminal vesicle by enzyme immunoassay


Bioorg Med Chem 17: 4459-65 (2009)


Article DOI: 10.1016/j.bmc.2009.05.018
BindingDB Entry DOI: 10.7270/Q2SX6D9B
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50295925
PNG
((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Show SMILES C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
Show InChI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+
PDB
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n/an/a 2.70E+3n/an/an/an/an/an/a



Karl-Franzens-Universit£t Graz

Curated by ChEMBL


Assay Description
Inhibition of COX2 in sheep placental vesicle by enzyme immunoassay


Bioorg Med Chem 17: 4459-65 (2009)


Article DOI: 10.1016/j.bmc.2009.05.018
BindingDB Entry DOI: 10.7270/Q2SX6D9B
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50295925
PNG
((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Show SMILES C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O
Show InChI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+
PDB
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n/an/a 1.00E+3n/an/an/an/an/an/a



Karl-Franzens-Universit£t Graz

Curated by ChEMBL


Assay Description
Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytes


Bioorg Med Chem 17: 4459-65 (2009)


Article DOI: 10.1016/j.bmc.2009.05.018
BindingDB Entry DOI: 10.7270/Q2SX6D9B
More data for this
Ligand-Target Pair