BDBM50296245 3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benzamide::CHEMBL552171
SMILES: Oc1ccc2[nH]cc(CCNC(=O)c3ccc(O)c(O)c3)c2c1
InChI Key: InChIKey=UYVJAIZMSPRFQW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Mus musculus (Mouse)) | BDBM50296245 (3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL | Assay Description Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysis | Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50296245 (3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL | Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation | Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70 | |||||||||||
More data for this Ligand-Target Pair |