BDBM50297420 (Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-yl)cyclopropyl)methanamine Hydrochloride::CHEMBL553224::N-methyl-1-((1S,2S)-2-(naphthalen-1-yloxy)-2-(thiophen-2-yl)cyclopropyl)methanamine hydrochloride

SMILES: CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1

InChI Key: InChIKey=YFHROOMCIQOYDA-KXBFYZLASA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50297420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine reuptake at norepinephrine transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin reuptake at serotonin transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin reuptake at serotonin transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine reuptake at norepinephrine transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake at dopamine transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50297420 ((Z)-N-Methyl-2-(naphthalen-1-yloxy)-2-(thiophen-2-...) Show SMILES CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H19NOS/c1-20-13-15-12-19(15,18-10-5-11-22-18)21-17-9-4-7-14-6-2-3-8-16(14)17/h2-11,15,20H,12-13H2,1H3/t15-,19-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	283	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon State University Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake at dopamine transporter				J Med Chem 52: 5872-9 (2009) Article DOI: 10.1021/jm900847b BindingDB Entry DOI: 10.7270/Q26Q1XBR
					More data for this Ligand-Target Pair